Gray nails, or onychomycosis, ointment dosage forms are generally not used to treat onychomycosis, and applicator dosage forms are generally used, including amorolfine and cyclopiazide. Nail fungal disease refers to the nail lesions caused by fungal invasion of the nail plate and under the nail. Oral antifungal medications are preferred for treatment, and topical medications are used for patients with contraindications to oral medications, patients who cannot tolerate oral medications, and patients with superficial nail fungal infections. Amorolfine has broad-spectrum antifungal activity and is sensitive to dermatophytes, and can be used to treat nail fungus disease with good efficacy. However, a small number of patients may experience site-of-use reactions, including skin irritation, erythema, and pruritus. Amorolfine is contraindicated in people who are allergic to the drug, pregnant women, and breastfeeding women avoid using the drug. Ciclopirox has the same strong antibacterial and bactericidal effect on dermatophytes, and it has the ability to penetrate the toenails, which can be used to treat nail fungus disease. Localized redness, itching, tingling and other irritating symptoms are occasionally seen during treatment and usually disappear on their own after stopping the drug. Ciclopirox is not recommended for use in children. The use of drugs are required under the guidance of medical professionals, if the topical application of drugs is ineffective, you need to go to the hospital in time, active treatment.