Quinolones: including pyrazole, haloperidol (norfloxacin), fludioxonate (enoxacin), ciprofloxacin (ciprofloxacin), etc. Among them, ciprofloxacin causes the incidence of central nervous system toxic side effects of 0.4% to 2.2%. Mainly dizziness, headache, anxiety, hand tremor, drowsiness, confusion, insomnia, hallucinations, epilepsy, etc. The treatment with ciprofloxacin 200 mg twice daily suddenly induced grand mal seizures on the 5th day of treatment, and a similar reaction occurred on the 7th day during the drip, which was not seen after stopping the drug. It is thought to be due to the drug blocking the binding of antiepileptic drugs to receptors in the brain, directly causing neurotoxicity. Recent studies have demonstrated that quinolones can inhibit the binding of the inhibitory transmitter γ-aminobutyric acid (GABA) to receptor sites in the brain, which increases excitability of the central nervous system, leading to spasms and induced seizures. Therefore, it is recommended that all drugs with a history of epilepsy be used with caution. Glucocorticoids: including cortisone acetate, hydrocortisone acetate, prednisone acetate (cortisone acetate), dexamethasone (flumethasone), betamethasone These drugs can induce psychiatric symptoms, euphoria, agitation, insomnia can occur with long-term heavy use, individual can induce psychotropic germs, children can cause convulsions. Epileptic patients can induce seizures, epileptic patients use or do not use such drugs with caution. Isoniazid: It is one of the most common anti-tuberculosis drugs, highly selective for Mycobacterium tuberculosis, with strong action and bactericidal effect. Use isoniazid with caution in epileptic patients. If the dose is too high or the duration of medication is too long, it can cause adverse neurological reactions, manifested as numbness, burning pain, tingling, insomnia, myalgias and induced convulsions in the limbs. The mechanism is related to isoniazid and vitamin B6 similar and compete for the same enzyme system or both combined into hydrazone excreted by urine, resulting in vitamin B6 deficiency, which can be prevented by vitamin B6. Tricyclic antidepressants: including promethazine, amitriptyline, meptyline, Ritalin, etc.. These drugs have a certain excitatory effect and can cause convulsions or induce seizures when applied in high doses or for longer periods of time. Promethazine is prohibited in patients with epilepsy, and other antidepressants should be used with caution. Anticholinesterase drugs: neostigmine bromide, neostigmine methosulfate, galantamine hydrobromide, are reversible anticholinesterase drugs, mainly through the inhibition of cholinesterase, acetylcholine accumulation and present M-like and N-like effects. It can cause muscle tremors and induce seizures, so it should be prohibited. Anthelmintics: Intestinal wormer (albendazole) is a highly effective, broad-spectrum, low-toxicity intestinal anthelmintic, effective against nematodes, trematodes and tapeworms, and should be contraindicated because it is likely to induce seizures.