In general, transaminase 110U/L is more serious. The reference range of transaminase is 0 to 40 U/L (the value may vary according to different measurement methods, and the local hospital shall prevail). Transaminase is widely present in human tissues, and is most abundant in hepatocytes, and when hepatocellular injury occurs, transaminase in hepatocytes will be released into the bloodstream, leading to elevation of serum transaminase. A transaminase test result of 110 U/L indicates the presence of hepatocellular injury, which may be associated with chronic active hepatitis, cirrhosis, hepatocellular carcinoma, alcoholic liver disease, and liver abscess. In general, the degree of transaminase elevation is positively correlated with the degree of hepatocellular necrosis; the more elevated the transaminase, the more hepatocellular damage. When the transaminase test result is 110 U/L, it indicates the presence of hepatocellular damage, and immediate medical attention is recommended for a definitive diagnosis and targeted treatment.