Patient: I am a major triple-positive patient, my liver function has always been normal, but the day before yesterday when I went for a checkup, I found out that my glutathione aminotransferase was very high, 739 U/L, and my glutathione aminotransferase was also 451 U/L. I went to the hospital for a checkup and was told to take antiviral treatment, and I was told to take tibifudin tablets and polyenyl phosphatidylcholine capsules. Will it have a bad effect on the fetus? Will it be passed on to the baby? What should I do to make it good for the fetus? Wang Lirong, Department of Gastroenterology, Nanjing Second Hospital: In the fifth month of pregnancy, the use of some liver-protective drugs will not have much effect on the fetus. Hepatitis B vaccine can be given at 0, 1, and 6 months after birth, and hepatitis B HVP immunoglobulin can be given at 0, 15, and 30 days for mother-to-child interruption, with the best reported efficacy of 90%. As for the use of tebivudine or not, there is a wide divergence of opinion among experts. After taking it, the mother-infant blockade rate can be improved, but the long-term effects on the fetus are unknown. Although it is a class B drug, it has little effect on the fetus, but it is not certain that there is no effect. I hope you will consider it clearly before taking it.