Drinking hiccups may be physiological factors, but also may be caused by gastroesophageal reflux disease or chronic gastritis and other diseases. 1. Physiological factors: drinking alcohol hiccups, usually due to alcohol stimulation caused by spasm of the diaphragm, the patient will drink alcohol uncontrollably hiccups phenomenon. 2. Gastroesophageal Reflux Disease (GERD): If the patient has irregular diet or improper diet for a long time, it may lead to the balance of the GERD mechanism breaking down, which may cause GERD, increased secretion of gastric acid, and hiccups when drinking alcohol under the stimulation of alcohol, which will appear in drinking. 3. Chronic gastritis: If the patient suffers from chronic gastritis, the alcohol in the wine will cause damage to the gastric mucosa or burning sensation, causing the symptoms of hiccups when drinking wine, accompanied by abdominal pain, vomiting, nausea and other manifestations. When patients drink occasionally hiccups phenomenon, may be physiological factors. If the patient often hiccups, should go to the hospital for examination, and according to the cause of treatment.