Chronic sinusitis has a better prognosis after active treatment and generally does not affect the patient’s life expectancy; however, if the patient does not receive treatment in a timely manner, it may cause intracranial infections, which can be life-threatening in severe cases. Chronic sinusitis often evolves from acute sinusitis, but also with sinus anatomical factors, trauma, odontogenic infection and other factors. Patients with chronic sinusitis are treated with medication, nasal glucocorticoids, such as budesonide nasal spray, antibacterial drugs, such as amoxicillin clavulanate potassium, cefuroxime, roxithromycin, etc.; mucus promoters, such as oleander, eucalyptus-pin intestinal soft capsule, etc.; nasal decongestants, such as hydroxymetholone hydrochloride nasal drops, which are usually used for no more than 7 days; and saline nasal rinses to clean up the nasal secretions. Sinuses with obvious structural abnormalities; polyps affecting the nasal sinus complex or sinus drainage; unsatisfactory symptomatic improvement after more than 12 weeks of standardized drug therapy; intracranial and intraorbital complications can be treated surgically, with open sinus surgery under nasal endoscopy. If chronic sinusitis undergoes standardized treatment, the prognosis is better and will not affect the survival time of the patient. However, if the patient fails to undergo timely treatment, it may cause intraorbital infection or intracranial infection, which may endanger the patient’s life in serious cases. It is recommended that patients with chronic sinusitis go to the hospital in time and actively cooperate with the doctor’s treatment, so as not to delay the condition.