p63+ stands for positive oncogene P63 protein. Oncogene P63 protein belongs to P53 homologous gene. p63 protein is a nuclear protein that regulates cell proliferation and apoptosis during the development of many malignant tumors, and is a sensitive and specific marker for myoepithelial cells. The oncogene P63 protein is positive in normal people, and the detection of P63 protein is an important indicator to determine the malignant degree of malignant tumors and the degree of metastatic recurrence. In recent years, with the development of immunohistochemistry technology, p63 as a marker has been gradually adopted in clinical diagnosis. the less staining of P63 protein, that is, when there is negative p63 protein, the higher the degree of malignancy of the tumor, the later the staging is, the more timely to the regular hospital, and the corresponding treatment under the guidance of the doctor.