The relative advantages of olmesartan ester amlodipine tablets include good antihypertensive effect; more stable control of blood pressure; reduce the occurrence of adverse reactions, increase the patient’s adherence to the medication, etc. The disadvantages are that the price is more expensive, the fixed dose of the compound preparation can not be flexible to increase or decrease the dose. Olmesartan ester amlodipine tablets is a kind of compound preparation composed of angiotensin II receptor blocker olmesartan ester and calcium channel blocker amlodipine. Olmesartan ester is a precursor drug, and the hydrolyzed olmesartan is a selective angiotensin II type 1 receptor antagonist, which blocks the vasoconstrictor effect of angiotensin II by selectively blocking the binding of angiotensin II to the α-receptor of vascular smooth muscle. Amlodipine is a dihydropyridine calcium antagonist, which exerts its blood pressure-lowering effect by inhibiting the transmembrane entry of calcium ions into vascular smooth muscle and myocardium. Olmesartan ester amlodipine tablets are mainly used for the treatment of essential hypertension and in adult patients whose blood pressure is not well controlled by treatment with olmesartan ester alone or amlodipine alone. The drug has mild adverse effects such as bronchitis and edema. It should be noted that the drug is contraindicated in cases of severe renal artery stenosis, renal failure, as well as hypersensitivity to the components of the drug. The drug should be taken strictly in accordance with medical advice.