The most serious lymphomas belong to Burkitt’s lymphoma, or lymphoblastic lymphoma. These two types of lymphomas are very malignant, that is, the lymphoma cells are primitive cells, so they are prone to extensive metastasis and progress very quickly, so it is necessary to use intense chemotherapy for both types of lymphomas to control the progression of the disease. The chemotherapy regimen is carried out according to that of high-grade lymphoma or leukemia, containing drugs such as vincristine, erythromycin, dexamethasone, cyclophosphamide, etc., and is done once every 3 weeks to kill the cancer cells, thus prolonging the patient’s life, and of course, allogeneic stem cell transplantation cases are needed if necessary to completely cure this highly malignant lymphoma.