Amoxicillin and aminophylline are two different drugs, the main difference in the indications, contraindications, adverse reactions and other aspects of the existence of different. 1. Amoxicillin: Amoxicillin is a penicillin antibacterial drug, mainly used for infectious diseases caused by sensitive bacteria, play a role in controlling infection. For people who are allergic to penicillin, it should be strictly avoided. Gastrointestinal reactions such as nausea and vomiting, allergic reactions such as skin rashes, and other rare adverse reactions such as thrombocytopenia and nervous excitement may occur after the use of the drug. 2. Aminophylline: Aminophylline is a smooth muscle relaxant, mainly used for asthma, wheezing bronchitis, obstructive emphysema and other relief of wheezing symptoms. For aminophylline allergy, active peptic ulcer, uncontrolled convulsive disease, as well as acute myocardial infarction with a significant decrease in blood pressure is strictly prohibited. The use of aminophylline may be accompanied by a variety of adverse reactions such as nausea, vomiting, agitation, insomnia, and even tachycardia. The difference between these two drugs is more, both need to be used under the guidance of a doctor, avoid self-medication, so as not to cause discomfort, or delay the condition.