Mucinous fibrosarcoma is a malignant tumor of mesenchymal origin, its tumor growth rate is relatively slow, and there is a certain chance that it can be cured in the early stage. The overall 5-year survival rate of mucinous fibrosarcoma is 60%～70%, which is related to its clinical typing, pathological type, physical condition, and treatment modality, and the earlier it is detected, the earlier it is treated, and the better the prognosis will be. Mucinous fibrosarcoma is now mostly manifested as a slow-growing painless mass, with a local recurrence rate as high as 50% to 60%, often with multiple recurrences, so it should be regularly reviewed after surgery, and is more common in older men. At present, the main clinical treatment for mucinous fibrosarcoma is surgical resection, plus postoperative radiotherapy and other comprehensive treatment means, the prognosis is better. Mucinous fibrosarcoma can be cured by early diagnosis and treatment, and standardized treatment under doctor’s guidance.