Diagnosed with congenital anal atresia combined with rectal perineal fistula, need to actively cooperate with the doctor’s treatment, common treatment methods for surgical treatment, specific should follow the doctor’s instructions. 1. low anal atresia combined with large fistula: patients in a certain period of time can still maintain normal defecation, can be born after 3-5 months and then surgery, the current treatment of low anorectal malformation of the surgical way more, commonly used for perineal anoplasty. 2. Treatment of middle and high anorectal atresia: the traditional classic operation is the preferred operation for the treatment of middle and high anorectal atresia; laparoscopic-assisted anorectoplasty has been applied later in the clinic, and there is some controversy, but there are also some advantages. When the diagnosis of congenital anal atresia combined with recto-perineal fistula is confirmed, the best treatment plan will be given according to the specific condition through the doctor’s evaluation, and it is recommended to follow the doctor’s instructions for standardized treatment.