The treatment of postoperative leukocytosis includes no special treatment, anti-infection treatment or drug withdrawal. Clinically, it is necessary to carry out targeted treatment according to the different causes of this situation in order to completely solve the situation of high white blood cells after surgery. 1. Surgery is a kind of trauma for the body itself, and the body will have a stress reaction in the face of trauma, which usually manifests itself as a slight increase in body temperature, which usually does not exceed 38℃. If the white blood cell increase is caused by stress reaction, there is no need for special treatment, and the white blood cell count will gradually return to normal after 3~5 days after the operation. 2. Postoperative bacterial infection can cause high white blood cells, postoperative infection may be wound infection, this situation needs timely debridement combined with antibiotic anti-infection treatment (levofloxacin, etc.); if non-wound infection, manifested as pneumonia, etc., then it is necessary to give timely antibiotic anti-infection treatment (cefepime, etc.). The white blood cells will gradually return to normal after treatment. 3. Find out whether the drugs that raise white blood cells are used during the operation, such as hormone drugs like dexamethasone. If they are used, the white blood cells can gradually return to normal after stopping the drugs for a period of time after the operation. If there is any increase in white blood cells after surgery, it is recommended to inform the doctor in charge of the case and follow the doctor’s instructions to carry out standardized and active treatment.