Itchy ankles have the following disease possibilities: the first one may be pigmented purpuric dermatosis, its etiology is not clear, it may be caused by increased capillary permeability and extravasation of red blood cells, which can appear as rust-colored petechiae and petechiae with a pepper-like distribution, some of which can fuse into patches, accompanied by a certain amount of itching. In treatment, you can take oral compound glycyrrhizin tablets as well as vitamin C capsules, rutin tablets and calcium carbonate D3 tablets, and apply topical dinaide ointment twice a day. The second case considers the possibility of contact dermatitis, mainly due to the application of creams causing well-defined edematous erythema, accompanied by itching such allergic conditions, in terms of treatment requires the application of mometasone furoate ointment, oral levocetirizine hydrochloride granules for anti-allergic treatment.