Cervical cancer is one of the most common gynecological malignant tumors, seriously threatening women’s health and life. Radiotherapy is one of the main means to treat cervical cancer, and intracavitary radiotherapy with external irradiation has been the standard treatment plan for middle and late stage cervical cancer. The complication rate of radiotherapy is high, especially the vaginal complication is the most prominent, which is clinically manifested as vaginal dryness, itching, increased secretion, etc., and even vaginal atrophy, adhesion and atresia may occur, which brings a lot of inconvenience to the patients’ life and reduces their quality of life, and the treatment of radiological vaginitis is more difficult, especially after the emergence of geriatric cervical cancer. At present, vaginal douching, antibiotics and estrogen are mostly used in clinical treatment, but the effect is poor and easy to recur. Therefore, in order to reduce the incidence of radiation vaginitis in cervical cancer and alleviate the pain of patients, the department draws on the theory of “prevention before disease” in Chinese medicine and believes that the treatment of radiation vaginitis should be intervened in the early stage, and puts forward the intervention strategy of early evidence-based nursing method of radiation vaginitis, and conducts clinical observation, and achieves certain efficacy, which is now reported as follows. The efficacy judgment standard of vaginitis occurs in the degree of vaginal mucosal reaction and vaginal cleanliness to assess. According to the grading standard of acute radiation reaction proposed by the American Radiation Oncology Research Center in 1992 [4]: 0 degree is no change; I degree is erythema or mild pain but does not need painkillers; II degree is patchy mucositis plasma oozing inflammation or moderate pain, need painkillers; III degree is fused fibrous mucositis or severe pain, need anesthesia; Ⅳdegree is ulceration hemorrhage or necrosis; evaluation of the degree of vaginal cleanliness [5]: I degree: Microscopy is dominated by vaginal bacilli and a large number of epithelial cells can be seen; Ⅱ degree: some vaginal bacilli, epithelial cells can also be seen, and there are some pus cells and miscellaneous bacteria; Ⅲ degree: only a small number of vaginal bacilli and epithelial cells can be seen, but there are a large number of pus cells and other miscellaneous bacteria; Ⅳdegree: there is no vaginal bacilli under the microscope, and it’s almost all pus cells and a large number of miscellaneous bacteria. Degree I and II were normal, and degree III and IV were abnormal. Discussion Cervical cancer patients in radiotherapy, the upper part of the vagina, the cervix is subjected to a higher volume, easy to cause radioactive reaction of the vaginal mucosa, so that the tumor tissue is necrotic and detached, gathered in the vagina, easy to trigger bacterial infection, especially in elderly patients with declining ovarian function, the body’s level of estrogen is reduced, the vaginal flora changes, itself easy to appear vaginitis symptoms. Evidence-based nursing is developed on the basis of evidence-based medicine, is that nurses should have sufficient scientific basis for all patient care. Suwen said: “Therefore, the sages do not treat the disease and treat the disease, do not treat the chaos and treat the chaos, this is also”, on this basis, so the use of traditional Chinese medicine, “before the disease first preventive” theory, put forward the early intervention method of evidence-based nursing, the formation of evidence-based members, evidence-based nursing related knowledge training, so that they master the knowledge of evidence-based nursing, and the early intervention method of evidence-based nursing. Evidence-based members were formed and trained in the relevant knowledge of evidence-based nursing, so that they could master the methods and necessary skills of evidence-based nursing. Then the evidence-based members put forward the evidence-based problems of the occurrence of cervical cancer radiation vaginitis, according to the clinical nursing experience and the patient’s condition, put forward three questions for evidence-based: the mechanism of the occurrence of radiation vaginitis is relatively clear, compared with the conventional nursing measures, is there a more targeted, better nursing measures; good psychological can have a positive effect on the treatment of cervical cancer radiotherapy patients have fear, anxiety, inferiority complex and other psychological, how to alleviate the psychological pressure of patients to cooperate with the various measures, how to reduce the psychological pressure of patients, and how to improve the psychological pressure of patients. How to alleviate the psychological pressure of patients to cooperate with the care and treatment; Cervical cancer patients are mostly elderly patients with poor cultural knowledge, how to strengthen the publicity of health education and knowledge to improve the compliance of patients. Due to the patients’ fear, low self-esteem and other psychological problems, fear of long-term torture and relatives cold fear of life is coming to the end, coupled with the long radiotherapy time, radiotherapy is easy to cause vaginitis, the patients are more prone to negative emotions, therefore, we choose nurses with rich professional knowledge and strong observation and expression ability to carry out the propaganda, to timely understand the patients’ psychological feelings in the aspect of the information, to take the initiative to care and comfort the patients, to explain patiently, to satisfy the patients’ need to be respected. Explanation, to meet the patient’s need to be respected, learn self-regulation, as far as possible to reduce the patient’s mental pressure, encourage them to maintain a good state of mind, actively cooperate with the treatment, and enhance the confidence to overcome the disease. From the research data of this study, after treatment, there were 13, 23, 9, 2, 0 cases of 0 degree, Ⅰ degree, Ⅱ degree, Ⅲ degree and Ⅳ degree of radioactive vaginal reaction in the evidence-based group, and 3, 12, 22, 7, 2 cases of 0 degree, Ⅰ degree, Ⅱ degree, Ⅲ degree and Ⅳ degree of radioactive vaginal reaction in the control group, the radioactive vaginal reaction of the patients in the evidence-based group was significantly weaker than that of the control group, with statistically significant differences (P<0.05); from the point of view of vaginal response, the patients' mental stress was reduced as much as possible, encouraging them to maintain a good attitude and actively cooperate with the treatment, and enhancing their confidence in overcoming the disease. 0.05); from the point of view of vaginal cleansing abnormality rate, the evidence-based group was only 19.16%, which was significantly lower than 63.04% in the control group, and the difference was statistically significant (P<0.05). This indicates that under the evidence-based nursing intervention, the incidence of cervical cancer radiation vaginitis and preventive measures of the patients in the evidence-based group were significantly improved, and this finding is consistent with the findings of Wang Jinghui et al.