Lumbar disc herniation combined with vertebral body slippage can be selected according to the degree of severity of the disease and appropriate treatment, including general treatment, drug treatment and surgical treatment. 1. General treatment: Improve bad habits in time and avoid prolonged sitting and standing. The symptoms can be improved by exercising the strength of the low back muscles, such as practicing swallow exercises and balance support. 2. Medication: When pain is caused by herniated lumbar disc combined with vertebral body slippage, it is recommended to take oral non-steroidal anti-inflammatory drugs, such as commonly used aspirin, celecoxib, indomethacin, and so on. 3. Surgery: It is more suitable for those who are in serious condition and fail to get good results from conservative treatment. They can consider disc decompression, spinal endoscopic disc nucleus pulposus removal, simple open disc nucleus pulposus removal, or hemilaminectomy, total laminectomy, and internal fixation surgery. Lumbar intervertebral disc herniation combined with vertebral body slippage can be treated in accordance with the above ways, but the specific should be combined with the degree of severity of the disease to choose, the specific should be under the guidance of a professional physician, don’t blindly use drugs.