Blood blisters in the mouth may be caused by either solid fire or deficiency fire, and should be treated under a doctor’s supervision. Real fire may be caused by inflammation of the heart fire, and in addition to mouth and tongue sores, there may be fever, thirst, heartburn, pain in the mouth and tongue, and redness of the face. Such patients can be treated with drugs such as Niu Huang Shang Qing Wan under the guidance of a physician. Deficiency fire is caused by insufficient heart yin or stomach yin (insufficient yin fluid in the stomach), and may cause low-grade fever in addition to mouth and tongue sores. Such patients can be treated with medicines such as Licorice Laxative Tang or Tianwang Xinshen Tonic Dan, Shashen Maidong Tang, and Bamboo Leaf Gypsum Tang, as instructed by the physician. Chinese medicine treatment should be based on evidence, please use the medicine under the guidance of a professional Chinese medicine practitioner, and do not use the medicine privately, as it may cause danger.