Alisartan is best paired with dihydropyridine calcium channel blockers and thiazide diuretics. Clinically, Alisartan belongs to angiotensin II receptor antagonist, after taking it can inhibit vasoconstriction, aldosterone release and sodium reabsorption, and also stimulate smooth muscle cell proliferation. It is mainly used in the treatment of mild and moderate essential hypertension. If the drug alone can not achieve the desired effect of lowering blood pressure, it is necessary to combine with other antihypertensive drugs. It is necessary to combine with other antihypertensive drugs for treatment, such as dihydropyridine calcium channel blockers, thiazide diuretics and so on. Common drugs include amlodipine, felodipine extended-release tablets, hydrochlorothiazide and so on. Usually, Alisatan may cause discomfort such as headache, dizziness, and elevated aminotransferases after taking it. It is contraindicated in women who are allergic to the components of the drug, breastfeeding in the middle and end stages of pregnancy. In the process of taking the drug, it is necessary to pay attention to renal artery stenosis, renal and hepatic insufficiency. Children and elderly patients need to use the drug under medical supervision. Usually after treatment with aliskatam alone, the effect of lowering blood pressure is not satisfactory. It is recommended to consult a doctor in time, and decide on the combination of drug programs and dosage after a comprehensive assessment of the condition by the doctor.