The clinical symptoms of pseudotuberculosis nodules were mainly cough, shortness of breath, and low fever. The images showed speckled nodular shadows in both lungs, a small amount of fluid in the right pleural cavity, a positive reaction on the PPD skin test, and a strong positive pleural fluid TB antibody. Pseudotuberculosis nodules in patients with a history of exposure to epidemic water and schistosomiasis in an infected area. The corn-like shadows of hematogenous pulmonary tuberculosis are uniform in distribution, size, and density, which are different from the nodules of schistosomiasis; blood tests show a significant increase in leukocyte count and eosinophil percentage, and positive stool hatching is a key differentiator. When the disease is suspected, a consultation with a specialist in parasite control should be sought or diagnostic treatment should be administered. The liver lesions caused by schistosomiasis are early hepatomegaly with corn-like yellow particles (egg nodules) on the surface. In the late stage, due to the proliferation of fibrous tissue around the portal vein branches, the liver becomes hard and shrinks, with nodules of different sizes on the surface, forming schistosomal cirrhosis. The establishment of portal collateral circulation causes varices in the lower esophageal veins and fundic veins, and the spleen becomes stagnant and enlarged due to portal hypertension, which can cause hypersplenism. Ectopic damage caused by schistosomes is most common in the lungs and brain. Cornular nodules and exudative inflammation around the nodules are seen in the lungs, and egg nodules and glial cell hyperplasia may appear in the brain at different times.