Hard bumps on the skin, accompanied by a little pain, may be related to skin boils, folliculitis and lymphadenitis, and are treated with anti-inflammatory drugs. 1. Skin boil is an inflammatory disease that occurs in the deep tissues of the hair follicle. Symptoms can be improved after anti-infective treatment, such as oral roxithromycin capsule and topical mupirocin ointment. Hot compresses on the skin of the affected area can also help promote the dissipation of inflammation within the skin. 2. Folliculitis is a superficial skin inflammation, in the treatment of topical antibiotic treatment, can relieve the symptoms, such as topical ichthyol cream, fusidic acid cream and so on. Oral antibiotics can be given if necessary. 3. Lymphadenitis is a disease that occurs when the lymph nodes are involved in an infection. Symptoms can be improved with oral anti-infective treatment, such as oral amoxicillin clavulanic acid potassium capsules, roxithromycin capsules and so on. In the process of using the medication must strictly follow the doctor’s instructions to use, continuous treatment with medication for a week without improvement, it must be timely consultation.