Bone cement is mainly used for support and immobilization. The chemical monomer of bone cement is polymethylmethacrylate, which is a bone adhesive. Bone cement can be filled into the bone defect site or between bone and prosthesis, and play the role of temporary support and fixation of bone, in addition to bone cement has the function of controlling local inflammation and improving the environment of bone healing. It is mainly used in artificial joint replacement surgery, vertebroplasty surgery, bone defect surgery and so on. Bone cement can cause allergic reactions such as decrease in blood pressure during the infusion process, in addition, bone cement is easy to leakage on the spinal cord or nerves to produce burns and allergies and a series of serious complications, for patients with allergies and intraoperative leakage of patients to stop the drug in time, to avoid the adverse consequences.