For flatulence after cholecystectomy, acid-suppressing drugs such as omeprazole and gastrointestinal stimulants such as mosapride citrate tablets may be taken to improve the symptoms of indigestion. 1. Acid suppressing drugs. After cholecystectomy, as a large amount of bile is released directly into the duodenum without concentration, the probability of bile refluxing into the stomach increases significantly, which may cause gastric flatulence. At this time, you can take omeprazole enteric-coated capsules, rabeprazole sodium enteric-coated tablets and other acid-suppressing agents to effectively protect the gastric mucosa. 2. Gastrointestinal stimulants. In addition to acid-suppressing medications, cholecystectomy flatulence can also use domperidone tablets, mosapride citrate tablets to enhance gastrointestinal dynamics, in order to help digestion. It is recommended that patients with post-cholecystectomy flatulence take the above medications under the guidance of a professional physician in order to effectively relieve the symptoms of indigestion.