The treatment of acute leukemia in the elderly needs to be individualized according to the specific condition, their own qualities, etc. Bone marrow transplantation can be considered for those with good physical conditions. Compared with young people, the treatment of acute leukemia in the elderly is more difficult, and it is necessary to determine the appropriate individualized treatment plan according to the age, stage of the disease, body function and other factors, and generally focus on prolonging the life span, reducing pain and improving the quality of life. Elderly people with acute leukemia can apply chemotherapy treatment and targeted drug therapy according to the specific typing of acute leukemia. If younger than 70 years old is in relatively good physical condition and has no other underlying disease, bone marrow transplantation can be considered for treatment. In addition, the elderly acute leukemia should focus on symptomatic supportive treatment, anemia, low platelets when taking blood transfusion therapy, etc.. At the same time to strengthen the nutritional diet of the elderly, to high protein food, etc.. For frail patients, it is also possible to enter the clinical trial of drugs, using new treatment methods, avoiding conventional chemotherapy. Because of the complexity of the treatment of acute leukemia in the elderly, it is recommended that standardized treatment be carried out under the guidance of a doctor.