Always wake up at night by urine consider different causes, for pathological factors caused by the need for different causes of medication, including sulfasalazine, tamsulosin, etc., should also improve the bad bedtime habits. The cause of waking up at night with urine may be cystitis, bladder mucosal lesions, need to use sulfadiazine, furotoxin anti-infection. Note that during the use of medication is prone to drug rash, may cause gastrointestinal irritation, pay attention to liver and kidney function impairment. Drug allergy, less than 2 months pediatrics, lactating women and other prohibited. If a man wakes up at night with urine, pay attention to prostatitis, prostate hyperplasia, it is recommended to improve the prostate ultrasound, prostate fluid examination and other clear. Tamsulosin can be taken orally to improve symptoms. The actual drug is commonly used during nausea and vomiting and other gastrointestinal adverse reactions, renal insufficiency, postural hypotension patients should be cautious. Under normal physiological circumstances, drinking too much water before going to bed, eating more water-containing fruits such as watermelon, can also appear in the middle of the night to wake up, can be improved by two hours before going to bed to ban water and food. Wake up at night by urine, improve lifestyle habits still have symptoms, it is recommended to consult a doctor in time to clarify the cause of the symptomatic treatment.