There is no basis for the effectiveness of trioxane water in treating varicose veins. The main mechanism of trioxide is to form hydrogen peroxide by reacting with body fluids to achieve local disinfection, sterilization, and promotion of wound healing. Varicose veins are mainly caused by poor venous return in the lower limbs, and the blood expands in the superficial veins in a tortuous manner, which over time results in serious sequelae such as trophic changes of the skin, hemorrhage and thrombosis. Therefore, trioxane water can not improve the problem of venous return in the root cause. However, trioxide can play a role by localizing the change of blood permeability, but the effect is not ideal and is not confirmed by clinical doctors and patients. Once the diagnosis of varicose veins is confirmed, it is not recommended to treat varicose veins with trioxide, which may induce phlebitis, venous ulcers and other serious adverse consequences, and to seek regular treatment in regular hospitals.