After the invasion of central squamous lung cancer from lower lobe to upper lobe, surgical resection of the tumor is the first step to be taken, and radiotherapy and chemotherapy are also needed to consolidate the treatment. 1. Surgical resection: central squamous lung cancer belongs to malignant tumors with high deterioration degree, therefore, when the primary lesion invades into the upper lobe from the lower lobe, it indicates that the scope of the tumor and the cancer cells has spread and increased, and it is necessary to completely remove the lesion as early as possible. Meanwhile, it is also necessary to check the surrounding lymph nodes and blood vessels for the presence of cancer cell infiltration and other complications during the cleaning surgery, so that the cancer cells and tissues can be completely removed as far as possible through the surgery. 2. Radiotherapy: if squamous carcinoma of lower lobe central type invades into upper lobe, it indicates that the cancer progresses faster and the condition is more serious, therefore, it is still necessary to cooperate with radiotherapy to consolidate the treatment after surgery. Chemotherapy drugs can be paclitaxel, doxorubicin or cisplatin. After central squamous lung cancer invades into the upper lobe, one should go to the hospital for examination in time, and under the guidance of doctors, resect the cancer as soon as possible and choose appropriate drugs for radiotherapy treatment, do not use drugs by oneself.