Early breast cancer does not have typical signs and symptoms, not easy to cause patients to pay attention, often found through physical examination or breast cancer screening. The following are typical signs of breast malignant tumor, be alert. 1. Breast lumps: 80% of breast cancer patients are first diagnosed with breast lumps. Patients often find lumps unintentionally, which are mostly single, hard, with irregular edges and less smooth surface. Most of the lumps are painless, only a few of them are accompanied by different degrees of hidden pain or tingling. 2.Nipple overflow. If blood, plasma, milk or pus comes out from nipple during non-pregnancy period, or if milk still comes out even if breastfeeding is stopped for more than half a year, it is called nipple discharge. There are many causes of nipple discharge, and common diseases include intraductal papilloma, breast hyperplasia, ductal dilatation and breast cancer. Hemorrhagic overflow of unilateral single hole should be further examined, and more attention should be paid if it is accompanied by breast lumps. 3.Skin changes. Skin changes caused by breast cancer can show various signs, the most common one is the adhesion with skin after tumor invades Cooper’s ligament, which will show “dimple sign”. If the cancer cells block the lymphatic vessels, “orange peel” will appear. In the advanced stage of breast cancer, the cancer cells infiltrate into the skin along lymphatic ducts, glandular ducts or fibrous tissues and grow to form “skin satellite nodules”. Abnormalities of nipple and areola. If the tumor is located in or close to the deep part of nipple, it can cause nipple retraction. When the tumor is far away from the nipple and the large ducts in the breast are invaded and shortened, it can also cause nipple retraction or elevation. Eczema-like cancer of nipple, i.e. Paget’s disease of nipple, manifested as itching, erosion, ulceration, crusting, flaking and burning pain of nipple skin, to nipple retraction. 5.Enlarged axillary lymph nodes. In occult breast cancer, no lump can be felt in physical examination of breast, and axillary lymph node enlargement is often the first symptom. More than 1/3 of breast cancer patients admitted in hospitals have axillary lymph node metastasis. Initially, the lymph nodes in the same side of the axilla may be enlarged, and the enlarged lymph nodes are hard, scattered and pushable. As the disease progresses, the lymph nodes gradually fuse and become adherent and fixed to the skin and surrounding tissues. In the advanced stage, metastatic lymph nodes can be felt on the clavicle and in the opposite axilla.