Ms. Yang, 23 years old, complained of premenstrual breast swelling and pain for 2 years. History: Breast distension and pain about one week before menstruation, including both hypochondriums, refusing to be pressed, emotional instability, anxiety and depression. Characteristics: Breast distension and pain about one week before menstruation, including both hypochondriums, pain refusing to be pressed, emotional instability, menstrual color purplish dark, with blood clots. Tongue and pulse diagnosis: dark red tongue, stringy pulse. Diagnostic analysis: Qi stagnation and blood stasis syndrome. The patient’s liver qi stagnation, unfavorable qi flow, and poor blood circulation caused breast distension and pain, which extended to the two hypochondriums, with pain that refused to be pressed. Unfavorable operation of the meridians and stagnation of menstrual blood led to purplish-colored menstruation with blood clots. Liver qi was uncomfortable, and the patient was emotionally unstable, anxious and depressed. Western medicine diagnosis: premenstrual tension syndrome Chinese medicine diagnosis: menstrual breast distension and pain (qi stagnation and blood stasis) Treatment: promoting qi and blood circulation, resolving blood stasis and relieving pain Treatment: prescription: danzhong, taichong, sanyinjiao, neiguan, period door. Stabbing and moxibustion: conventional operation of all points, laxative method. Efficacy: treatment began one week before menstruation, symptoms disappeared after two menstrual cycles. This case: danzhong belongs to ren chi points, eight points of the gas will, regulating the role of qi significant; tai chong for the swelling meridian original point, have swollen swelling, clear the liver and nourish the role of blood; three yin jiao is the spleen, liver, kidney meridian junction point, can be strengthened to ingest blood, tonifying the liver and benefit the kidneys, for the treatment of gynecological diseases of the key points. Neiguan and Ximen move Qi and relieve pain. Treatment should be started 5-7 days before menstruation when symptoms have not yet appeared, for better prevention and treatment.