Large red hard bumps on the body bitten by insects belong to the symptomatic manifestation of insect bite dermatitis. It can be treated with topical medication and oral medication if necessary. 1. Topical drugs: red hard lumps appear locally after being bitten by insects, if there is obvious oozing, boric acid solution can be given wet compresses, astringent effect, can reduce oozing. If there is no ooze, you can use glycerine lotion, mometasone furoate cream and other drugs to apply. If secondary bacterial infection, antibiotics such as mupirocin ointment can also be used in combination. 2. Oral medication: If the local itching is obvious, fexofenadine hydrochloride, olopatadine hydrochloride, levocetirizine hydrochloride and so on can be given to relieve the symptoms of itching. If necessary, with vitamin C, calcium gluconate, can reduce the permeability of capillaries. After being bitten by insects on the body, if the patient’s symptoms are more serious, it is recommended to go to the hospital in time and ask the doctor to deal with it accordingly, so as to avoid delaying the condition. The above drugs need to be used in accordance with medical advice.