Shiquan Dajian Pill can treat lower limb weakness and knee pain caused by deficiency of qi and blood; however, lower limb pain and weakness caused by other reasons are not treated by Shiquan Dajian Pill. The ingredients of Shiquan Dajian Pill are Codonopsis, Poria, Atractylodes macrocephala, Radix Angelicae Sinensis, Rhizoma Ligustici Chuanxiong, Radix Paeoniae Alba, Radix Astragali, Radix Rehmanniae Praeparatae, Cinnamon; it can be used to treat deficiency of qi and blood, pale face, dizziness, self-sweating (involuntary sweating during the daytime, which is aggravated with the slightest movement), tiredness and weakness of the body, and lack of warmth in the limbs. If the deficiency of qi and blood for a long time leads to the loss of nourishment of the meridians, then there can be pain and weakness in the lower limbs and knees, which can be treated with Shiquan Dazhuang Pill. However, it is more common for this symptom to appear as impotence paralysis, which should be treated with other medicines. For example, Damp-Heat Underflow (Dampness and Heat evils invading the intestines, bladder, pubic area, lower limbs, etc.) syndrome, impotence paralysis, showing pain in the tendons and bones, or impotence and weakness of the two feet, or redness and pain in the feet and knees. If the two feet are numb or swollen and painful like the heat of fire, impotence and weakness, use San Miao Pill. The adverse reactions and contraindications of Shiquan Dajian Pill, Ermiao Pill and Sanmiao Pill are not clear, and it is recommended to use the medication under the guidance of a doctor. There are many diseases and types of symptoms that can cause lower limb knee pain and weakness, so if you use the wrong medicine, it may delay the condition or even aggravate it. It is recommended to consult a doctor and avoid self-medication.