High transaminases in babies may be due to viral hepatitis, infectious mononucleosis and other conditions, which can be treated with general therapy, medication and so on. 1. Viral hepatitis: Viral hepatitis can cause liver cell necrosis and elevated transaminases. Commonly by type A viral hepatitis, type B viral hepatitis, type C viral hepatitis, etc. At this time, in addition to general treatment, such as appropriate rest, eat more carbohydrates, lean meat, fish, beans and other foods, mainly to drug therapy, such as lamivudine, entecavir, adefovir and so on. 2. Infectious mononucleosis: mostly caused by EBV infection, in addition to liver function abnormalities, can be caused by fever, sore throat, enlarged tonsils and swollen lymph nodes in the neck, etc. At this time, the use of antiviral drugs, such as ganciclovir, acyclovir, interferon alpha and so on. All of the above drugs need to be used under the guidance of a doctor, avoid self-medication. There are many other reasons for high aminotransferase in babies. It is recommended to consult a doctor in time, and after evaluation by a specialist, improve the relevant examination and give targeted treatment or therapy.