After minimally invasive surgery for appendicitis, hardness around the wound is generally normal, or it may be inflammation, a reaction to the wound stitches that appear as a knot, and so on. 1. Normal reaction: after appendicitis surgery, the wound will appear scarring during the recovery period, hardening around the wound is a normal phenomenon, due to tissue proliferation during the wound healing process. 2. Inflammation: If the patient’s wound becomes hard, accompanied by redness, swelling, pain, and even patients with fever and other symptoms, it may be due to inflammation, then you can follow the doctor’s instructions, with iodophor to carry on the local wiping or the use of amoxicillin capsules and other antibacterial drugs. 3. Knot reaction: If the patient’s wound becomes hard, but not accompanied by other symptoms, it may be due to the knot reaction of the suture line at the wound, appearing foreign body granuloma, you can follow the doctor’s instructions to take out the thread or to strengthen the dressing change. Symptoms are relieved after suture removal. It is recommended that the patient seek medical treatment in time and take appropriate treatment according to the doctor’s advice, do not make judgment on your own to avoid causing unnecessary symptoms.