Toothache oral metronidazole whether there is an effect need to be based on the specific causes of toothache after judgment, periodontitis or wisdom teeth peri-coronitis and so on have an effect, but pulpitis or periapical inflammation when there is no effect. Patients with toothache if there is a periodontitis, wisdom teeth peri-coronitis and other diseases, taking metronidazole treatment generally have some effect, can help anti-inflammatory anti-bacterial, to avoid aggravation of the symptoms, but if it is the emergence of pulpitis, peri-coronitis and other diseases, taking metronidazole treatment drugs can not penetrate into the pulp tissues, generally do not achieve a better effect, you can choose to carry out endodontic treatment, remove the nerve and relieve the pain. Usually try to eat less sugary food, but also need to pay attention to oral hygiene, diligent brushing and rinsing, but also need regular oral examination. The use of drugs should follow the doctor’s instructions, do not use without authorization.