Early pregnancy refers to the period before 14 weeks of gestation, when premature rupture of membranes is usually recommended for termination of pregnancy, timely induction of labor and prophylactic anti-infective treatment. Premature rupture of membranes refers to the natural rupture of membranes before labor, and the clinical manifestation is that the pregnant woman suddenly feels more fluid coming out of the vagina, and the amount of vaginal fluid increases when the abdominal pressure is increased. As the fetus is not fully developed in early pregnancy, no treatment can be expected after premature rupture of membranes because the survival rate of the fetus is extremely low. The pregnancy should be terminated in a timely manner, and if left untreated, chorioamnionitis is likely to occur, so prophylactic anti-infective treatment is needed at the same time as evacuation of the uterus. It is recommended that women with preterm rupture of membranes in early pregnancy should seek medical treatment in a timely manner, as the success rate of expectant treatment at this time is extremely low, and the condition may be delayed, jeopardizing the mother’s life.