Pain when breathing after having a bile duct puncture can be seen in normal cases because of the local trauma caused by the puncture, and the failure of local anesthetics can lead to increased pain, which can be relieved after general adaptation, but it can also be seen in abnormal cases, and the common causes are: poor biliary drainage, cholestatic peritonitis, and so on. 1. Poor biliary drainage: poor biliary drainage usually leads to increased pressure in the bile duct and pain when breathing, which should be further examined under the guidance of the doctor, and then re-commissioning the drainage tube or placing a new drainage tube to relieve the patient’s symptoms. 2. Biliary peritonitis: poor bile drainage can cause bile leakage, or puncture punctured the extrahepatic bile ducts, causing bile extravasation, resulting in biliary peritonitis, which is a very serious situation, the patient will experience acute pain, should be punctured in time to drain the abdominal cavity, flush the infected area, or re-implantation of a new drainage tube. Usually, patients should always pay attention to their physical condition, maintain a good mood, eat a light diet, promptly explain to the doctor if there are any uncomfortable symptoms, and cooperate with the doctor for active treatment. If it hurts when breathing after bile duct puncture, it is recommended to go to the hospital in time.