Fatty liver is a condition in which there is a large accumulation of fat in the liver, causing steatopathologic changes. Fatty liver is clinically categorized as mild, moderate, or severe depending on how much fat accumulates in the liver. In cases where ultrasound shows a fatty liver with liver nodules, the liver nodules are usually not due to steatosis of the liver. The pathologic change in liver nodules is fibrous hyperplasia of the liver tissue, whereas fatty liver is steatosis of the liver cells. Liver nodules are irreversible changes, and a large number of nodules present in the liver may further progress to cirrhosis. In the early stage of fatty liver, the liver can be restored to the normal state through timely regulation of blood lipids. For liver nodules with normal liver function in the early stage, it is necessary to improve liver ultrasound or even imaging enhancement examination, including enhanced CT or enhanced magnetic resonance, in order to further clarify the nature of liver nodules and exclude the possibility of malignant nodules in the liver.