Wearing socks with strangulation marks may be edema, or it may be due to mechanical compression. There are many causes of edema in the legs, the common ones are glomerulonephritis or nephrotic syndrome of renal disease, cirrhosis of the liver, heart valve disease or cardiac insufficiency, hypothyroidism, etc. All these diseases of the internal medicine system may lead to edema in the lower limbs, which may cause strangulation marks when wearing socks. If the socks are too small or too tight, the strangulation marks may be caused by squeezing of the socks. If the socks are too tight, it may lead to poor blood flow and localized edema, so it is recommended to replace the socks with appropriate ones. If patients find edema, it is recommended to go to the regular hospital in a timely manner, complete the examination to determine the cause of the disease, and then give targeted treatment or treatment under the guidance of the doctor.