The feeling of bugs crawling in the buttocks may be caused by pinworms, perianal eczema, neurodermatitis and so on. 1. Pinworm disease: a parasitic disease caused by human pinworm parasites in the human intestine. Its main manifestation is itching around the anus, which is more obvious at night and can be accompanied by sleep disturbance, emotional irritability, teeth grinding, abdominal pain, lack of appetite and other symptoms. It can be manifested as a feeling of bugs crawling in the buttocks. 2. Perianal eczema: it is a chronic inflammatory reaction of the skin around the anus caused by a variety of internal and external factors. The main manifestations are perianal rash, intense itching, often due to excessive scratching or hot water scalding, and redness, swelling, oozing, erosion. Its can also lead to the feeling of bugs crawling in the buttocks. 3. Neurodermatitis: It is a kind of chronic inflammatory, skin neurological dysfunction dermatitis characterized by paroxysmal intense itching and mossy skin. If issued in the buttocks or perianal, can also lead to the buttocks have the feeling of crawling insects. There are many other causes of the feeling of bugs crawling on the buttocks, which should be taken seriously, timely consultation, identification of the cause of the disease, and follow the doctor’s instructions for further treatment or therapy.