Alcohol consumption is not recommended in the presence of hypothyroidism. Thyroxine has an important regulatory role in maintaining the body’s protein, sugar and fat metabolism. In hypothyroidism, because of insufficient thyroxine, it can lead to the accumulation of mucopolysaccharides, resulting in mucinous edema of the skin, muscles and other tissues, and can especially induce hypothyroid cardiomyopathy. Alcohol consumption can further affect the body’s energy metabolism and also increase the burden on the heart, leading to further damage to the heart muscle. Hypothyroidism also tends to induce changes such as hypoglycemia and hyperlipidemia, while alcohol also tends to induce hypoglycemia and can also aggravate the cardiovascular damage caused by hyperlipidemia. Hypothyroidism usually requires lifelong replacement therapy with thyroxine tablets and other medications. When thyroid function is maintained to normal levels after treatment, a small amount of alcohol can be considered, and strict abstinence from alcohol is required until thyroid function is restored.