Senna leaf, also known as Senna leaf and Senna leaf. It is sweet in taste, bitter, cold in nature, and belongs to the large intestine meridian, with the effect of removing heat and stagnation, laxative and diaphoretic, mainly for the treatment of heat accumulation in the stomach and intestines, stagnation of food, chest and abdominal distension, ascites, constipation, etc. It is mainly used in the treatment of gastrointestinal bleeding, chronic renal failure, epidemic hemorrhagic fever, constipation, acute pancreatitis, toxic intestinal paralysis, etc. before and after medical, surgical and gynecological procedures, as well as before lumbar and abdominal X-ray examinations and intestinal preparation before surgery. However, because of its serious adverse reactions, clinical application is somewhat restricted and requires strict control of its dose. Common clinical adverse reactions are: 1, addictive: long-term use of senna patients with constipation will be withdrawal symptoms, manifested as distraction, insomnia, anxiety, general discomfort, even pain or ants, dilated pupils, hot flushed face, anorexia, fever, yawning, rapid breathing, increased blood pressure, weight loss, etc. 2, malignant changes in blood pressure: elderly patients taking senna can appear Headache and frequent vomiting, sharp rise or fall in blood pressure, and even shock, which can be recovered after stopping the dose and symptomatic treatment. 3, neurotoxic reaction: manifested as facial numbness, dizziness, urinary and fecal incontinence, itching sensation, and painful hyperalgesia of varying degrees within the trigeminal nerve distribution area. 4, gastrointestinal bleeding: patients manifest severe pain in the upper abdomen, vomiting coffee-colored liquid and passing black stools, etc. 5, jaundice: manifested as dizziness The jaundice is characterized by dizziness, fatigue, weakness, fever, yellow urine, yellow sclera, enlarged liver and spleen, decreased hemoglobin, and significantly increased urobilinogen. 6.