Whether a sub-solid nodule 4.5mm x 2.6mm in the upper lobe of the right lung needs surgery or not needs to be combined with other indicators to make a comprehensive judgment. Generally, benign signs can be treated without surgery; highly suspicious of malignant lesions, surgical resection is recommended. 1. Do not need surgery: the nodule is relatively small, located under the pleura, with smooth edges, without causing thickening of the neighboring pleura, and all the indicators belong to benign signs judged by other indicators of CT, so it does not need surgical treatment, and it only needs to be reviewed regularly by CT. 2. Surgery is needed: nodules with malignant signs, visible lobes, burrs, vacuoles, pleural pulling and other malignant symptoms, highly suspicious of malignant lesions, need to be surgically resected under the risk assessment of the thoracic surgeon. If the corresponding nodule continues to increase in size during the review process, it is necessary to consult a doctor in time for observation, and after the diagnosis of the lesion condition is confirmed, standardized treatment should be carried out under the guidance of the clinician to avoid delaying the condition.