Numbness of the hands and legs may be related to physiological factors, or may be caused by cervical spondylosis, peripheral neuropathy, cerebrovascular lesions and other factors. 1. Physiological factors: commonly found in sleeping, due to incorrect sleeping posture, resulting in prolonged pressure on one side of the body, resulting in the pressure side of the body’s blood flow is not smooth, may cause numbness of one side of the hands and legs. 2. Cervical spondylosis: prolonged over-low head may induce cervical spondylosis, when cervical spondylosis aggravates, it may compress the spinal cord, which will lead to numbness of the hands and legs, and may be accompanied by limb weakness, walking difficulties and other symptoms. 3. Peripheral neuropathy: long time presence of diabetes may induce peripheral neuropathy, which will cause numbness in hands and feet, and may be accompanied by tingling, loss of sensation, burning sensation and other symptoms. 4. Cerebrovascular lesions: for example, acute cerebral infarction or cerebral hemorrhage may lead to unilateral numbness of hands and legs, which may be accompanied by dizziness, headache, nausea, vomiting and other abnormal manifestations. Numbness of the hands and legs and other abnormal manifestations, may be the existence of abnormal conditions, it is recommended to consult a doctor for examination and treatment, to avoid causing adverse consequences.