The flakes in the nipples during pregnancy may be caused by dry skin, inflammation or allergy, which can be improved by keeping the skin moist and applying medication. If the skin is too dry to cause flakes in the nipples during pregnancy, you need to pay attention to the local hygiene first. When there is dry skin in the nipple, you can use a hot towel to apply warm compresses to the local area and scrub, and then you can apply breast milk or topical application of vitamin E cream to relieve it. If necessary, you can also apply erythromycin ointment, which can play the role of lubricant cleaning. If it is caused by local inflammation, when the symptoms are mild, you can apply erythromycin ointment under the guidance of the doctor to improve, if necessary, oral erythromycin capsule combined medical treatment. If it is caused by allergy, you can first apply glycerine lotion to alleviate the symptoms, to avoid too dry skin leading to aggravation of the symptoms. If necessary, you can also take oral loratadine or cetirizine treatment. The flakes in the nipples during pregnancy should also be considered for other reasons such as tumor factors, if the symptoms continue to be unrelieved, accompanied by local pain and itching and other phenomena, you can go to the hospital for examination and treatment for the cause. Drugs should be applied under the guidance of a doctor.