Melanin deposits on both sides of the nose need to be removed in a way that depends on the specific cause, such as acne, hyperpigmentation, mite infections, etc. After a clear diagnosis, general treatment, medication, and laser treatment are taken. 1. Acne: patients with closed acne on both sides of the nose, the oil secretions accumulated in the pores oxidize and blacken at the point of contact with the air, resulting in visual blackening on both sides of the nose. This condition can be treated with regular chemical resurfacing in a formal medical institution, while using antibiotic ointment, such as erythromycin ointment, as prescribed by the doctor, as well as doing a good job of daily skin cleansing and care. 2. Hyperpigmentation: Black pigmentation on both sides of the nose may be due to hyperpigmentation after acne inflammation. This situation requires strict sunscreen, if necessary, you can go to the hospital through photorejuvenation, fractional laser way to improve the pigmentation; can also be used externally hydroquinone cream or translucent acid serum and other drugs to lighten the pigmentation. 3. Cui hair increase: heredity, endocrine system diseases and other reasons can lead to the bilateral nose at the increase in cui hair coarsening, resulting in visual black phenomenon. This situation can consider laser hair removal to improve. 4. mite infection: mite infection on both sides of the nose, can also cause the phenomenon of melanosis, should be mite treatment, daily use of sulfur soap to clean the local, at the same time to the daily necessities for sun exposure, especially bed sheets, pillows, quilts and other items. The black pigmentation on both sides of the nose needs to be taken according to the specific cause of the treatment, if you need to use drugs, you should go to the regular medical institutions to follow the doctor’s instructions, not to be used indiscriminately, so as not to lead to adverse consequences.