Atrophic gastritis has the potential to develop cancer. In the development of chronic gastritis to gastric cancer, atrophy, intestinal epithelial hyperplasia, and heterogeneous hyperplasia are regarded as precancerous lesions of gastric cancer. Atrophic gastritis, which is characterized by atrophy of the gastric mucosa and a decrease in the number of glands, is very common and the most important cause of the disease is Helicobacter pylori infection. Helicobacter pylori infection will lead to delayed or aggravated inflammatory response, which may lead to intestinal epithelial hyperplasia or heterogeneous hyperplasia in atrophic gastritis, and ultimately lead to cancer. If you have atrophic gastritis, you should actively treat and regularly review to prevent cancer, the first priority is to eradicate H. pylori, currently recommended quadruple therapy, the commonly used treatment program is amoxicillin + clarithromycin + omeprazole + bismuth bismuth potassium citrate. Combined with abdominal pain, belching and other symptoms, should be symptomatic treatment. In addition, daily life should pay attention to a light diet, mainly easy to digest food, avoid spicy, stimulating, smoky, pickled food, etc., pay attention to rest, avoid staying up all night, etc.. If the situation is serious, it is necessary to seek medical treatment in time to avoid delaying the condition and affecting the treatment.