Carvedilol and Metoprolol both have certain therapeutic effects on essential hypertension, due to the individual differences in the condition, it can not be said that which one has the best effect, according to the patient’s specific situation to choose the medication. Carvedilol is suitable for symptomatic heart failure and can also be used in the treatment of essential hypertension, this drug has strong cardioprotective and neuroprotective effects, can reduce the resistance of the body circulation and pulmonary circulation, effective control of high blood pressure; after taking it, there may be mild dizziness, headache, fatigue, bradycardia, gastrointestinal discomfort and other adverse reactions; contraindicated in pregnancy and breastfeeding women. Metoprolol is mainly used for mild and moderate essential hypertension, also used in the treatment of angina pectoris, myocardial infarction, arrhythmia and other diseases; after taking it, there may be bradycardia, hypotension, dizziness, headache, dry mouth, nausea, lack of appetite, rash and other adverse reactions; heart rate is too low, moderate-to-severe heart failure, pregnant women and breastfeeding women are prohibited. The above two drugs shall be by the regular hospital, under the guidance of a professional physician, according to the patient’s specific circumstances to choose to use the drug, after taking, if you feel any discomfort, to consult a doctor in a timely manner.