Quadruple drugs have a kind of no more, can not stop for 2 days, quadruple drugs are used to remove Helicobacter pylori, the medication course is 10~14 days, if one kind of drug is not available, you need to replenish in time, stopping 2 days of drugs may affect the therapeutic effect, so it is not recommended to stop the medication. The quadruple combination of drugs includes two antibiotics, a bismuth agent, and a proton pump inhibitor. Bismuth can assist the proton pump inhibitor, which has the effect of inhibiting gastric acid, inhibiting bacterial growth, and protecting the gastric mucosa, together with the two antibiotics, it can inhibit the growth of H. pylori, so as to achieve the effect of removing H. pylori. If one of the drugs is discontinued during the medication period, it may result in incomplete removal of H. pylori. Therefore, it is recommended that the medication should be used on time during the treatment period, and if you find that one of the medications has been used up, you should seek medical advice to replenish the missing medication. It is recommended to use quadruple drugs under the guidance of a doctor and avoid unauthorized use of drugs to avoid adverse consequences. Please do not take medication on your own to avoid delaying your condition.