EGFR is the epidermal growth factor receptor, and EGFR mutation is more accurate in squamous lung cancer. Lung squamous carcinoma is a pathological type of non-small cell lung cancer, EGFR is the epidermal growth factor receptor, the test found that the mutation is more accurate, the emergence of EGFR is a mutation often suggests that the metastasis of the tumor cells, infiltration, but also can be used for lung squamous carcinoma targeted therapy medication guidance. Early stage of squamous lung cancer is mainly treated by surgery, and can also be assisted by chemotherapy, targeted therapy, radiotherapy, immunotherapy and so on. To achieve early detection, early diagnosis and early treatment is the key to improve the prognosis. It is important to pay attention to regular review in daily life, monitor the changes of symptoms, and go to the hospital in time when uncomfortable symptoms appear.