The correct name of neonatal impetigo is impetigo, which is often caused by bacterial infection, and can be treated by strengthening local care, and topical or oral medication if necessary. 1. strengthen care: neonatal impetigo, pay attention to maintain local cleanliness and hygiene, avoid scratching with hands because of itching, so as not to aggravate the infection, etc.. 2. medication: (1) topical drugs: pustules unbroken can be used externally with glycerite lotion, which can relieve the itching feeling of patients. For lesions with less exudation, mupirocin ointment and other antibiotic ointment can be used topically, which can play the role of antibacterial. (2) Oral medication: If topical medication is ineffective, antibiotics such as cefixime can be prescribed for anti-infective treatment. It is recommended that newborns with impetigo go to the hospital in time and follow the doctor’s instructions for treatment to avoid delaying the condition.