Huangkui capsule has a certain role in the treatment of urinary protein, Huangkui capsule is a more commonly used proprietary Chinese medicine, which is a kind of auxiliary application in the clinic as the treatment of urinary protein, and it is also widely used. In fact, in the domestic treatment of kidney disease, usually also utilizes Chinese herbs, Chinese patent medicines, including Huangkui capsule. The main ingredient of wasabi capsule is wasabi flower, which has the effect of preserving kidney, replenishing qi and lowering urinary protein, moreover, wasabi capsule has the efficacy of clearing heat and relieving dampness, detoxifying and eliminating swelling, which is suitable for the patients with the manifestation of damp-heat evidence of chronic nephritis, for example, the patients are accompanied by swelling, lumbago, hematuria, proteinuria, yellowish and greasy tongue coating and other symptoms at the same time. In the clinic, the adverse reaction of this drug is mainly taking huangkui capsule may appear digestive symptoms, manifested as epigastric distension and discomfort, nausea, vomiting, diarrhea and so on, so this drug has a certain digestive tract stimulation problem, usually to be taken after meals, pregnant female patients can not use huangkui capsule. For the treatment of kidney disease, this drug only plays an adjunctive therapeutic effect, the treatment of urinary protein should also be specific to clarify the cause, for the cause of the treatment, different causes of urinary protein, the treatment program is not the same, such as primary glomerulonephritis need to do a renal puncture biopsy, according to the results of the biopsy to decide on the next step in the treatment program, if necessary, the choice of the use of glucocorticoids impact therapy, and immunosuppressive agents, The application of total tretinoin, while the Chinese patent medicines such as Huangkui capsule only play an auxiliary role.